Articles & Publications Curated By Dr. Edward J. Zuckerberg on P.Gingivalis & the Oral-Systemic Connection
Overview Articles
- Porphyromonas gingivalis and Its Systemic Impact: Current Status National Library of Medicine, Nov. 2020
- New Approaches to Combat P. gingivalis Biofilms
Journal of Oral Microbiology, March 2017 - The Role of P. gingivalis Outer Membrane Vesicles in Periodontal Disease & Related Systemic Diseases Frontiers in Cellular and Infection Microbiology, Jan. 2021
- P. gingivalis: An Overview of a Periodontopathic Pathogen Below the Gum Line Frontiers in Microbiology, Feb. 2016
- The Gingipains of P. gingivalis
Wikipedia
Mental Health
- Association Between Periodontal Disease and Mental Health Outcomes ScienceDirect, June 2021
- P. gingivalis Induces Depression
National Library of Medicine, October 2019 - P. gingivalis and Cardinal Symptoms of Depression
Biological Psychiatry, May 2019
Heart Disease
- The Link Between P. gingivalis and Myocardial Infarction 2023
- Impact of P. gingivalis on Foam Cell Formation and Atherosclerosis July 2023
- P. gingivalis and Atrial Fibrillation
Hiroshima University, May 2025 - Oral Biofilms and Their Connection to Systemic Health
European Society of Medicine, September 2022
Alzheimer’s Disease and Dementia
- Gum Disease May Be the Cause of Alzheimer’s. Here’s How to Avoid It New Scientist, January 2019
- P. gingivalis Outer Membrane Vesicles as a Major Driver of Neuropathogenesis in Alzheimer’s Disease Journal of Alzheimer’s Disease, July 2021
- Gingipains: Exploring Their Impact on Overall Health Beyond Periodontal Disease RDH, June 2024
- We May Finally Know What Causes Alzheimer’s Disease and How to Stop It New Scientist, January 2019
- The Cause of Alzheimer’s Disease Could Be Coming From Inside Your Mouth ScienceAlert, November 2022
- P. gingivalis in Alzheimer’s Disease: Evidence of Disease Causation Science Advances, January 2019
- The Link Between Periodontitis and Alzheimer’s Disease: Emerging Clinical Evidence ScienceDirect, March 2023
Additional Topics
Diabetes
Periodontitis as a Promoting Factor of Type 2 Diabetes: Current Evidence and Mechanisms
International Journal of Oral Science, June 2023
Eye
Invasion of Human Retinal Pigment Epithelial Cells by P. gingivalis
May 2020
Digestive Tract Tumors
P. gingivalis and Digestive Tract Tumors
Pathology & Oncology Research, March 2021
Oral Cancer
P. gingivalis and Oral Cancer
Frontiers in Oncology, 2019
Liver
Association Between P. gingivalis and Liver Disease
Journal of Clinical Periodontology, August 2021
Gut and Inflammatory Bowel Disease
P. gingivalis Exacerbates Inflammatory Bowel Disease
Pathogens, January 2022
